Development of PDMS-glass hybrid microchannel mixer composed of micropillars and micronozzles
- Authors
- 고용준; 하승모; 김현중; 이동호; 안유민
- Issue Date
- Jun-2007
- Publisher
- MMD-JSME
- Keywords
- PDMS-glass hybrid micromixer; micropillar; micronozzle; PVP solution; mixing efficiency
- Citation
- International Conference on Advanced Technology in Experimental Mechanics 2007
- Indexed
- OTHER
- Journal Title
- International Conference on Advanced Technology in Experimental Mechanics 2007
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/43438
- DOI
- 10.1299/jsmeatem.2007.6._P-36-1_
- Abstract
- In this research, a microchannel type mixer composed of micropillars and micronozzles was
developed for effective mixing of biochemical samples. To estimate the performance of the new designed
micromixer, flow patterns were simulated using the computational fluid dynamics software. The simulation showed that the mixing efficiency increased from 87.9% to 97.5% as the flow rate varied from 50 to
500 Pl/min. When liquid were injected into the fabricated micromixer, it was difficult to prime the microchannel because of hydrophobicity of PDMS surface. To overcome this problem, the inside of the micromixer was coated with PVP (polyvinylpyrrolidone). It was found that over 0.25 wt.% PVP concentration in the DI water solution was recommendable. After appropriate PVP coating, the DI water and the
mixture of blue dye and DI water were mixed in the fabricated micromixer and the mixing efficiency was
measured. The mixing efficiency increased from 68.8% to 92.6% as the flow rate increased from 50 to
500 Pl/min. The new micromixer showed very good mixing performance when the flow rate was over
300 Pl/min. Due to the simple structure and uncomplicated fabrication process, the proposed micromixer
can be easily integrated to the micro total analysis system (µ-TAS) or lab-on-a-chip.
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