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Cleavage agents for soluble oligomers of amyloid beta peptides
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Suh, Junghun | - |
| dc.contributor.author | Yoo, Sang Ho | - |
| dc.contributor.author | Kim, Min Gyum | - |
| dc.contributor.author | Jeong, Keunhong | - |
| dc.contributor.author | Ahn, Jae Young | - |
| dc.contributor.author | Kim, Myoung-Soon | - |
| dc.contributor.author | Chae, Pil Seok | - |
| dc.contributor.author | Lee, Tae Yeon | - |
| dc.contributor.author | Lee, Jaehwa | - |
| dc.contributor.author | Lee, Jeongkuk | - |
| dc.contributor.author | Jang, Yun Ah | - |
| dc.contributor.author | Ko, Eun Hwa | - |
| dc.date.accessioned | 2021-06-23T21:02:08Z | - |
| dc.date.available | 2021-06-23T21:02:08Z | - |
| dc.date.created | 2021-01-21 | - |
| dc.date.issued | 2007 | - |
| dc.identifier.issn | 1433-7851 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/44397 | - |
| dc.description.abstract | (Chemical Equation Presented) Clearing the mind: Peptide-cleaving agents for amyloid β-42 (Aβ42) oligomers (see scheme), the intermediate neurotoxic species in the pathology of Alzheimer's disease, have been obtained from a combinatorial library built using the CoIII complex of 1,4,7,10-tetraazacyclododecane as the reaction center. Effective cleavage of the Aβ42 oligomers occurs at submicromolar concentrations of the agents. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | John Wiley & Sons Ltd. | - |
| dc.title | Cleavage agents for soluble oligomers of amyloid beta peptides | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Chae, Pil Seok | - |
| dc.identifier.doi | 10.1002/anie.200702399 | - |
| dc.identifier.scopusid | 2-s2.0-34848913126 | - |
| dc.identifier.wosid | 000249752200020 | - |
| dc.identifier.bibliographicCitation | Angewandte Chemie - International Edition, v.46, no.37, pp.7064 - 7067 | - |
| dc.relation.isPartOf | Angewandte Chemie - International Edition | - |
| dc.citation.title | Angewandte Chemie - International Edition | - |
| dc.citation.volume | 46 | - |
| dc.citation.number | 37 | - |
| dc.citation.startPage | 7064 | - |
| dc.citation.endPage | 7067 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.subject.keywordPlus | PROTEIN A-BETA | - |
| dc.subject.keywordPlus | ALZHEIMERS-DISEASE | - |
| dc.subject.keywordPlus | IN-VIVO | - |
| dc.subject.keywordPlus | BRAIN | - |
| dc.subject.keywordPlus | HYPOTHESIS | - |
| dc.subject.keywordPlus | A-BETA-40 | - |
| dc.subject.keywordAuthor | Alzheimer&apos | - |
| dc.subject.keywordAuthor | s disease | - |
| dc.subject.keywordAuthor | amyloid beta peptides | - |
| dc.subject.keywordAuthor | combinatorial chemistry | - |
| dc.subject.keywordAuthor | drug design | - |
| dc.subject.keywordAuthor | peptide cleavage | - |
| dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/anie.200702399 | - |
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Related Researcher
- Chae, Pil Seok
- ERICA 공학대학 (DEPARTMENT OF BIONANO ENGINEERING)