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A preparative isolation and purification of arctigenin and matairesinol from Forsythia koreana by centrifugal partition chromatography
- Authors
- Chul Young Kim; Mi-Jeong Ahn; Jinwoong Kim
- Issue Date
- Mar-2006
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- arctigenin; centrifugal partition chromatography; Forsythia koreana; matairesinol; preparative chromatography
- Citation
- JOURNAL OF SEPARATION SCIENCE, v.29, no.5, pp 656 - 659
- Pages
- 4
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF SEPARATION SCIENCE
- Volume
- 29
- Number
- 5
- Start Page
- 656
- End Page
- 659
- ISSN
- 1615-9306
1615-9314
- Abstract
- Centrifugal partition chromatography was applied to separate arctigenin and matairesinol from Forsythia koreana extract with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (5:5:5:5 v/v). Using this method, arctigenin and matairesinol were successfully separated from partially purified F. koreana extracts in only one step. The purities of isolated compounds were determined to be over 90% by HPLC analysis.
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Related Researcher
- Kim, Chul Young
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)