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Synthesis of carbocyclic 1-[4-(hydroxymethyl)cyclopent-2-enyl]-1,2,4-triazole-3-carboxamide and its derivatives
- Authors
- An, Gwang-il; Rhee, Hakjune
- Issue Date
- Dec-2002
- Publisher
- Marcel Dekker Inc.
- Keywords
- carbocyclic nucleoside; Pd(0)-catalyzed; coupling reaction; carbocyclic ribavirin analogues
- Citation
- Nucleosides, Nucleotides and Nucleic Acids, v.22, no.4, pp 437 - 451
- Pages
- 15
- Indexed
- SCIE
SCOPUS
- Journal Title
- Nucleosides, Nucleotides and Nucleic Acids
- Volume
- 22
- Number
- 4
- Start Page
- 437
- End Page
- 451
- ISSN
- 1525-7770
- Abstract
- The synthesis of carbocyclic 1-[4-(hydroxymethyl)cyclopent-2-enyl]-1,2,4-triazole-3-carboxamide (6a) and its derivatives was achieved from triol 10 in excellent overall yield. This route involves a Pd(0)-catalyzed coupling reaction as a key step.
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Related Researcher
- Rhee, Hak june
- ERICA 공학대학 (ERICA 에너지바이오학과)