A F acile synthesis of cis-4-amino-2-cyclopentene-1-methanol, a key intermediate for the synthesis of carbocyclic nucleosides
DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Gwang-Il | - |
dc.contributor.author | Rhee, Hak june | - |
dc.date.accessioned | 2021-06-24T01:04:03Z | - |
dc.date.available | 2021-06-24T01:04:03Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2002-01 | - |
dc.identifier.issn | 1525-7770 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/46859 | - |
dc.description.abstract | A number of carbocyclic nucleosides can be synthesized from ( +cis-4-amino-2-cyclopentene-1 -methanol (3). Carbocyclic amino alcohol 3 is a key intermediate that makes possible the efficient synthesis of the carbocyclic nucleosides. In this study we wish to report an efficient synthesis of carbocyclic amino alcohol 3 from inexpensive and readily available starting material. The synthetic route employed cyclopentadiene (4) as a starting material and proceeded in 38% overall yield through 6 steps involving a hetero Diels-Alder reaction and an aza-Claisen rearrangement. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Marcel Dekker Inc. | - |
dc.title | A F acile synthesis of cis-4-amino-2-cyclopentene-1-methanol, a key intermediate for the synthesis of carbocyclic nucleosides | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rhee, Hak june | - |
dc.identifier.doi | 10.1081/NCN-120006531 | - |
dc.identifier.scopusid | 2-s2.0-0036010562 | - |
dc.identifier.wosid | 000175059700006 | - |
dc.identifier.bibliographicCitation | Nucleosides, Nucleotides and Nucleic Acids, v.21, no.1, pp.65 - 72 | - |
dc.relation.isPartOf | Nucleosides, Nucleotides and Nucleic Acids | - |
dc.citation.title | Nucleosides, Nucleotides and Nucleic Acids | - |
dc.citation.volume | 21 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 65 | - |
dc.citation.endPage | 72 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.subject.keywordPlus | DIELS-ALDER CYCLOADDITIONS | - |
dc.subject.keywordPlus | ANTIVIRAL AGENT CARBOVIR | - |
dc.subject.keywordPlus | NITROGEN BOND-CLEAVAGE | - |
dc.subject.keywordPlus | AMINO-ACID SYNTHESIS | - |
dc.subject.keywordPlus | ASYMMETRIC-SYNTHESIS | - |
dc.subject.keywordPlus | EFFICIENT SYNTHESIS | - |
dc.subject.keywordPlus | SULFONYL CYANIDES | - |
dc.subject.keywordPlus | REARRANGEMENT | - |
dc.subject.keywordPlus | RESOLUTION | - |
dc.subject.keywordPlus | 1592U89 | - |
dc.identifier.url | https://www.tandfonline.com/doi/full/10.1081/NCN-120006531 | - |
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