Nanoscale graphene oxide-induced metallic nanoparticle clustering for surface-enhanced Raman scattering-based IgG detection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ali, Ahmed | - |
dc.contributor.author | Hwang, Eun Young | - |
dc.contributor.author | Choo, Jaebum | - |
dc.contributor.author | Lim, Dong Woo | - |
dc.date.accessioned | 2021-06-22T12:21:28Z | - |
dc.date.available | 2021-06-22T12:21:28Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/6781 | - |
dc.description.abstract | Surface-enhanced Raman scattering (SERS) has been of great interest to advance sensitive optical biosensors. Clustered metallic nanoparticles as SERS nanoprobes are important to detect specific biomolecules with ultra-sensitivity. We report herein that the cluster formation of gold nanoparticles (GNPs) was induced by nanoscale graphene oxides (NGOs) with 120 nm to develop a new class of SERS nanotags for biosensing. The GNPs with 4-mercaptopyridine as a Raman reporter were modified with 1-pyrenemethylamine to introduce hydrophobic moieties on the surfaces and were complexed with NGOs via noncovalent interactions of pi-pi stacking and van der Waals interactions, resulting in the formation of NGO-GNP clusters (NGO-GNPCs). The NGO-GNPCs increased the SERS signal 3- to 4-fold higher than that of the individual GNPs due to enhancement of the electromagnetic field at the interstices of the GNPs. As a proof of concept, the NGO-GNPCs as SERS nanoprobes and magnetic beads (MBs) were developed to detect immunoglobulin G (IgG). Sandwich-type immunocomplexes of the NGO-GNPCs, IgG, and MBs were formed, representing a linear correlation between Raman intensity and IgG concentration, and a limit of detection of 0.6 pM. It suggests that the NGO-GNPCs as SERS nanoprobes could open a new avenue for highly sensitive SERS-based biosensing. (C) 2017 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.title | Nanoscale graphene oxide-induced metallic nanoparticle clustering for surface-enhanced Raman scattering-based IgG detection | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Dong Woo | - |
dc.identifier.doi | 10.1016/j.snb.2017.07.140 | - |
dc.identifier.scopusid | 2-s2.0-85027518653 | - |
dc.identifier.wosid | 000414151800022 | - |
dc.identifier.bibliographicCitation | SENSORS AND ACTUATORS B-CHEMICAL, v.255, pp.183 - 192 | - |
dc.relation.isPartOf | SENSORS AND ACTUATORS B-CHEMICAL | - |
dc.citation.title | SENSORS AND ACTUATORS B-CHEMICAL | - |
dc.citation.volume | 255 | - |
dc.citation.startPage | 183 | - |
dc.citation.endPage | 192 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | SPECTROSCOPIC DETECTION | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | NANOPROBES | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordPlus | IMMUNOASSAY | - |
dc.subject.keywordPlus | SUBSTRATE | - |
dc.subject.keywordPlus | BACTERIA | - |
dc.subject.keywordPlus | NETWORK | - |
dc.subject.keywordAuthor | Nanoscale graphene oxide | - |
dc.subject.keywordAuthor | Metallic nanoparticles | - |
dc.subject.keywordAuthor | Clusters | - |
dc.subject.keywordAuthor | Surface enhanced Raman scattering | - |
dc.subject.keywordAuthor | IgG detection | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0925400517313552?via%3Dihub | - |
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