Four New Acylated Iridoid Glycosides from the Aerial Part of Veronicastrum sibiricum and Their Antioxidant Response Element-Inducing Activity
- Authors
- Kim, Myeong Il; Kim, Chul Young
- Issue Date
- Jan-2018
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Veronicastrum sibiricum (L; ) Pennell; Scrophulariaceae; acylated iridoid glycosides; antioxidant response element; ARE-luciferase reporter assay
- Citation
- CHEMISTRY & BIODIVERSITY, v.15, no.1, pp.1 - 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY & BIODIVERSITY
- Volume
- 15
- Number
- 1
- Start Page
- 1
- End Page
- 8
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/6906
- DOI
- 10.1002/cbdv.201700447
- ISSN
- 1612-1872
- Abstract
- Four new (1 - 4) and one known (5) acylated iridoid glycosides were isolated from the aerial parts of Veronicastrum sibiricum (L.) Pennell. The chemical structures of the isolated compounds were determined to be 3,4-dicinnamoyl-6-O-rhamnopyranosyl-10-O-bergaptol-5,7-bisdeoxycynanchoside (1), 3,4-dicinnamoyl-6-O-rhamnopyranosylpaulownioside (2), 2,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (3), 3,4-dicinnamoyl-6-O-rhamnopyranosylaucubin (4), and 3,4-dicinnamoyl-6-O-rhamnopyranosylcatalpol (5) using spectroscopic techniques. Among these compounds, compound 5 increased antioxidant response element (ARE) luciferase activity.
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