Conventional method of transverse aortic constriction in mice
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo, Jimeen | - |
dc.contributor.author | Chepurko, Vadim | - |
dc.contributor.author | Hajjar, Roger J. | - |
dc.contributor.author | Jeong, Dongtak | - |
dc.date.accessioned | 2021-06-22T13:02:25Z | - |
dc.date.available | 2021-06-22T13:02:25Z | - |
dc.date.created | 2021-01-22 | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 1064-3745 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/7909 | - |
dc.description.abstract | Transverse aortic constriction is a widely used surgical model to reflect the progression from cardiac hypertrophy to heart failure states due to left ventricular pressure overload in mice. It produces afterload increase on the left ventricle in which compensated hypertrophy initially occurs in the first 2, weeks. This develops into maladaptive remodeling of the left ventricle and atrium, leading to heart failure. This model is useful for cardiac studies since transverse aortic constriction can be consistently replicated and has low surgical mortality. Additionally, the gradual progression to cardiac failure makes it a valuable method to evaluate the efficacy of potential therapeutic intervention. We introduce this chapter to offer practical approaches to facilitate a simple methodology for transverse aortic constriction. © Springer Science+Business Media, LLC, part of Springer Nature 2018. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Humana Press Inc. | - |
dc.title | Conventional method of transverse aortic constriction in mice | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jeong, Dongtak | - |
dc.identifier.doi | 10.1007/978-1-4939-8597-5_14 | - |
dc.identifier.scopusid | 2-s2.0-85050152335 | - |
dc.identifier.bibliographicCitation | Methods in Molecular Biology, v.1816, pp.183 - 193 | - |
dc.relation.isPartOf | Methods in Molecular Biology | - |
dc.citation.title | Methods in Molecular Biology | - |
dc.citation.volume | 1816 | - |
dc.citation.startPage | 183 | - |
dc.citation.endPage | 193 | - |
dc.type.rims | ART | - |
dc.type.docType | Book Chapter | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | animal experiment | - |
dc.subject.keywordPlus | animal model | - |
dc.subject.keywordPlus | aortic constriction | - |
dc.subject.keywordPlus | echocardiography | - |
dc.subject.keywordPlus | experimental cardiovascular disease | - |
dc.subject.keywordPlus | heart left ventricle overload | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | mouse | - |
dc.subject.keywordPlus | mouse model | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | operation duration | - |
dc.subject.keywordPlus | postoperative period | - |
dc.subject.keywordPlus | transverse aortic constriction | - |
dc.subject.keywordPlus | animal | - |
dc.subject.keywordPlus | aorta | - |
dc.subject.keywordPlus | cardiomegaly | - |
dc.subject.keywordPlus | complication | - |
dc.subject.keywordPlus | disease exacerbation | - |
dc.subject.keywordPlus | disease model | - |
dc.subject.keywordPlus | heart failure | - |
dc.subject.keywordPlus | heart ventricle | - |
dc.subject.keywordPlus | ligation | - |
dc.subject.keywordPlus | microsurgery | - |
dc.subject.keywordPlus | pathophysiology | - |
dc.subject.keywordPlus | procedures | - |
dc.subject.keywordPlus | surgery | - |
dc.subject.keywordPlus | systole | - |
dc.subject.keywordPlus | Animals | - |
dc.subject.keywordPlus | Aorta | - |
dc.subject.keywordPlus | Cardiomegaly | - |
dc.subject.keywordPlus | Constriction | - |
dc.subject.keywordPlus | Disease Models, Animal | - |
dc.subject.keywordPlus | Disease Progression | - |
dc.subject.keywordPlus | Echocardiography | - |
dc.subject.keywordPlus | Heart Failure | - |
dc.subject.keywordPlus | Heart Ventricles | - |
dc.subject.keywordPlus | Male | - |
dc.subject.keywordPlus | Mice | - |
dc.subject.keywordPlus | Microsurgery | - |
dc.subject.keywordPlus | Systole | - |
dc.subject.keywordAuthor | Heart failure | - |
dc.subject.keywordAuthor | Hypertrophy | - |
dc.subject.keywordAuthor | Microsurgery | - |
dc.subject.keywordAuthor | TAC | - |
dc.subject.keywordAuthor | Transverse aortic constriction | - |
dc.identifier.url | https://link.springer.com/protocol/10.1007/978-1-4939-8597-5_14 | - |
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