A novel anthrapyridone diamine-based probe for selective and distinctive Cu2+ and Hg2+ sensing in aqueous solution; utility as molecular logic gates
- Authors
- Kumar, Ashwani; Kumar, Subodh; Chae, Pil Seok
- Issue Date
- Oct-2020
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Fluorescence; Anthrapyridone-diamine; Cu2+ or Hg2+ sensing; Ratiometric; Colorimetric
- Citation
- DYES AND PIGMENTS, v.181, pp.1 - 14
- Indexed
- SCIE
SCOPUS
- Journal Title
- DYES AND PIGMENTS
- Volume
- 181
- Start Page
- 1
- End Page
- 14
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/836
- DOI
- 10.1016/j.dyepig.2020.108522
- ISSN
- 0143-7208
- Abstract
- A newly synthesized anthrapyridone-based diamine (probe 1) having two metal ion binding sites exhibited selective and sensitive sensing of Cu2+ or Hg2+ among various metal ions. Upon addition of the metal ion, the probe 1-containing solution vividly changed color, enabling visual detection of each metal ion (Cu2+ or Hg2+) without requiring any instruments. A ratiometric approach insensitive to environmental interference provided limit of detections (LODs) of 1.0 and 2.0 mu M for Cu2+ and Hg2+ sensing, respectively. The green fluorescence emission of probe 1 was entirely (Cu2+) or partially (Hg2+) quenched in the presence of the metal ion, yielding an observed fluorescence-based LOD (5/200 nM for Cu2+/Hg2+). Thus, probe 1 showed a dual responsiveness for detection of the metal ion. A model probe (2) with only a single metal binding site was ineffective at sensing the metal ion (Cu2+ or Hg2+) under the same conditions, demonstrating that the presence of the two binding sites in probe 1 is essential for the sensitive detection of the metal ion. The DFT calculations suggest binding of the metal ion to the probe with a stoichiometry of 1:1 or 2:1 (M2+ : probe). Probe 1 was also effective at detecting a small amount of Cu2+ in live HeLa cells or real samples such as tap and lake waters. The UV-Vis. absorbance results of probe 1 with Cu2+ and Hg2+ enabled us to build 'NOR-YES-INHIBIT' molecular logic gates. The metal ion sensing system presented here was extensively investigated by various techniques including UV-visible, fluorescence, NMR spectroscopy, DFT calculations, FE-SEM, and DLS.
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