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Functionalization of Graphene Oxide and its Biomedical Applications

Authors
Nanda, Sitansu SekharPapaefthymiou, Georgia C.Yi, Dong Kee
Issue Date
3-Sep-2015
Publisher
TAYLOR & FRANCIS INC
Keywords
graphene oxide; graphene oxide functionalization; bioimaging; drug delivery; biosensor; environment
Citation
CRITICAL REVIEWS IN SOLID STATE AND MATERIALS SCIENCES, v.40, no.5, pp.291 - 315
Journal Title
CRITICAL REVIEWS IN SOLID STATE AND MATERIALS SCIENCES
Volume
40
Number
5
Start Page
291
End Page
315
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10135
DOI
10.1080/10408436.2014.1002604
ISSN
1040-8436
Abstract
Graphene oxide (GO) offers interesting physicochemical and biological properties for biomedicine due to its versatility, biocompatibility, small size, large surface area, and its ability to interact with biological cells and tissues. GO is a two-dimensional material of exceptional strength, unique optical, physical, mechanical, and electronic properties. Ease of functionalization and high antibacterial activity are two major properties identified with GO. Due to its excellent aqueous processability, amphiphilicity, surface functionalization capability, surface enhanced Raman scattering (SERS), and fluorescence quenching ability, GO chemically exfoliated from oxidized graphite is considered a promising material for biological applications. In addition, due to -* transitions, a low energy is required for electron movement, a property important in Biosensor and Bioimaging applications of GO. In this article, we present an overview of current advances in GO applications in biomedicine and discuss future perspectives. We conclude that GO is going to play a vital role in Biomedical applications in the near future.
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