Potential Fluid Biomarkers for the Diagnosis of Mild Cognitive Impairment
DC Field | Value | Language |
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dc.contributor.author | Vo Van Giau | - |
dc.contributor.author | Bagyinszky, Eva | - |
dc.contributor.author | An, Seong Soo A. | - |
dc.date.available | 2020-02-27T02:22:25Z | - |
dc.date.created | 2020-02-04 | - |
dc.date.issued | 2019-09-01 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1020 | - |
dc.description.abstract | Mild cognitive impairment (MCI) is characterized by a level of cognitive impairment that is lower than normal for a person's age, but a higher function than that that observed in a demented person. MCI represents a transitional state between normal aging and dementia disorders, especially Alzheimer's disease (AD). Much effort has been made towards determining the prognosis of a person with MCI who will convert to AD. It is now clear that cerebrospinal fluid (CSF) levels of A beta 40, A beta 42, total tau and phosphorylated tau are useful for predicting the risk of progression from MCI to AD. This review highlights the advantages of the current blood-based biomarkers in MCI, and discusses some of these challenges, with an emphasis on recent studies to provide an overview of the current state of MCI. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.subject | ALZHEIMERS ASSOCIATION WORKGROUPS | - |
dc.subject | PLASMA MICRORNA BIOMARKERS | - |
dc.subject | CEREBROSPINAL-FLUID | - |
dc.subject | AMYLOID-BETA | - |
dc.subject | PHOSPHORYLATED-TAU | - |
dc.subject | PRECLINICAL DEMENTIA | - |
dc.subject | DISEASE PROGRESSION | - |
dc.subject | NATIONAL INSTITUTE | - |
dc.subject | GENETIC-VARIATION | - |
dc.subject | CLUSTERIN LEVELS | - |
dc.title | Potential Fluid Biomarkers for the Diagnosis of Mild Cognitive Impairment | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000486888400081 | - |
dc.identifier.doi | 10.3390/ijms20174149 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.20, no.17 | - |
dc.identifier.scopusid | 2-s2.0-85071754683 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.citation.volume | 20 | - |
dc.citation.number | 17 | - |
dc.contributor.affiliatedAuthor | Vo Van Giau | - |
dc.contributor.affiliatedAuthor | Bagyinszky, Eva | - |
dc.contributor.affiliatedAuthor | An, Seong Soo A. | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | mild cognitive impairment | - |
dc.subject.keywordAuthor | Alzheimer&apos | - |
dc.subject.keywordAuthor | s disease | - |
dc.subject.keywordAuthor | biomarkers | - |
dc.subject.keywordAuthor | diagnosis | - |
dc.subject.keywordPlus | ALZHEIMERS ASSOCIATION WORKGROUPS | - |
dc.subject.keywordPlus | PLASMA MICRORNA BIOMARKERS | - |
dc.subject.keywordPlus | CEREBROSPINAL-FLUID | - |
dc.subject.keywordPlus | AMYLOID-BETA | - |
dc.subject.keywordPlus | PHOSPHORYLATED-TAU | - |
dc.subject.keywordPlus | PRECLINICAL DEMENTIA | - |
dc.subject.keywordPlus | DISEASE PROGRESSION | - |
dc.subject.keywordPlus | NATIONAL INSTITUTE | - |
dc.subject.keywordPlus | GENETIC-VARIATION | - |
dc.subject.keywordPlus | CLUSTERIN LEVELS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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