Potential Fluid Biomarkers for the Diagnosis of Mild Cognitive Impairment
- Authors
- Vo Van Giau; Bagyinszky, Eva; An, Seong Soo A.
- Issue Date
- 1-Sep-2019
- Publisher
- MDPI
- Keywords
- mild cognitive impairment; Alzheimer' s disease; biomarkers; diagnosis
- Citation
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.20, no.17
- Journal Title
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Volume
- 20
- Number
- 17
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1020
- DOI
- 10.3390/ijms20174149
- ISSN
- 1422-0067
- Abstract
- Mild cognitive impairment (MCI) is characterized by a level of cognitive impairment that is lower than normal for a person's age, but a higher function than that that observed in a demented person. MCI represents a transitional state between normal aging and dementia disorders, especially Alzheimer's disease (AD). Much effort has been made towards determining the prognosis of a person with MCI who will convert to AD. It is now clear that cerebrospinal fluid (CSF) levels of A beta 40, A beta 42, total tau and phosphorylated tau are useful for predicting the risk of progression from MCI to AD. This review highlights the advantages of the current blood-based biomarkers in MCI, and discusses some of these challenges, with an emphasis on recent studies to provide an overview of the current state of MCI.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 바이오나노대학 > 바이오나노학과 > 1. Journal Articles
- 산업·환경대학원 > 산업환경공학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1020)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.