ScholarWorks@Gachon

Detailed Information

Cited 20 time in webofscience Cited 20 time in scopus
Metadata Downloads

Synthesis and biological evaluation of chalcone analogues as protective agents against cisplatin-induced cytotoxicity in kidney cells

Full metadata record
DC Field Value Language
dc.contributor.authorLee, Dahae-
dc.contributor.authorKim, Ki Hyun-
dc.contributor.authorMoon, Sung Won-
dc.contributor.authorLee, Heesu-
dc.contributor.authorKang, Ki Sung-
dc.contributor.authorLee, Jae Wook-
dc.date.available2020-02-28T09:43:20Z-
dc.date.created2020-02-06-
dc.date.issued2015-05-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10540-
dc.description.abstractChalcone analogues were prepared and evaluated for any renoprotective effects on cisplatin-treated cultured kidney cells (LLC-PK1); two chalcone analogues exhibited a potent renoprotective effect. In an additional study, we demonstrated that the blocking of MAPKs-p53-caspase-3 signaling cascade plays an important role in mediating the protective effect of these compounds against oxidative cytotoxicity in cultured LLC-PK1 cells. (C) 2015 Published by Elsevier Ltd.-
dc.language영어-
dc.language.isoen-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.subjectINDUCED APOPTOSIS-
dc.subjectRENAL DAMAGE-
dc.subjectINJURY-
dc.subjectANTICANCER-
dc.subjectNEPHROTOXICITY-
dc.subjectINVOLVEMENT-
dc.subjectDERIVATIVES-
dc.subjectPATHWAYS-
dc.subjectGINSENG-
dc.subjectSTRESS-
dc.titleSynthesis and biological evaluation of chalcone analogues as protective agents against cisplatin-induced cytotoxicity in kidney cells-
dc.typeArticle-
dc.type.rimsART-
dc.description.journalClass1-
dc.identifier.wosid000353205000022-
dc.identifier.doi10.1016/j.bmcl.2015.03.026-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.25, no.9, pp.1929 - 1932-
dc.identifier.scopusid2-s2.0-84933497715-
dc.citation.endPage1932-
dc.citation.startPage1929-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume25-
dc.citation.number9-
dc.contributor.affiliatedAuthorLee, Dahae-
dc.contributor.affiliatedAuthorKang, Ki Sung-
dc.type.docTypeArticle-
dc.subject.keywordAuthorChalcone-
dc.subject.keywordAuthorCisplatin-induced nephrotoxicity-
dc.subject.keywordAuthorRenoprotection-
dc.subject.keywordAuthorMAPKs-p53-caspase-3-
dc.subject.keywordPlusINDUCED APOPTOSIS-
dc.subject.keywordPlusRENAL DAMAGE-
dc.subject.keywordPlusINJURY-
dc.subject.keywordPlusANTICANCER-
dc.subject.keywordPlusNEPHROTOXICITY-
dc.subject.keywordPlusINVOLVEMENT-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusPATHWAYS-
dc.subject.keywordPlusGINSENG-
dc.subject.keywordPlusSTRESS-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Files in This Item
There are no files associated with this item.
Appears in
Collections
한의과대학 > 한의예과 > 1. Journal Articles
Show simple item record

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kang, Ki Sung photo

Kang, Ki Sung
College of Korean Medicine (Premedical course of Oriental Medicine)
Read more

Altmetrics

Total Views & Downloads

CONTACT US

RSS_1.0 RSS_2.0 ATOM_1.0

1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114

COPYRIGHT 2020 Gachon University All Rights Reserved.

Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.

BROWSE

한국어