Probe-pin device for optical neurotransmitter sensing in the brain
- Authors
- Kim, M.H.; Song, K.D.; Yoon, H.; Park, Y.; Choi, S.H.; Lee, D.-S.; Shin, K.-S.; Hwang, H.-I.; Lee, U.
- Issue Date
- 2015
- Publisher
- SPIE
- Keywords
- microspectrometer; nanostructure; neurotransmitter; Optical neural sensing; surface plasmonic resonance
- Citation
- Proceedings of SPIE - The International Society for Optical Engineering, v.9434, no.January
- Journal Title
- Proceedings of SPIE - The International Society for Optical Engineering
- Volume
- 9434
- Number
- January
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10940
- DOI
- 10.1117/12.2085610
- ISSN
- 0277-786X
- Abstract
- Development of an optical neurotransmitter sensing device using nano-plasmonic probes and a micro-spectrometer for real time monitoring of neural signals in the brain is underway. Clinical application of this device technology is to provide autonomous closed-loop feedback control to a deep brain stimulation (DBS) system and enhance the accuracy and efficacy of DBS treatment. By far, we have developed an implantable probe-pin device based on localized field enhancement of surface plasmonic resonance on a nanostructured sensing domain which can amplify neurochemical signals from evoked neural activity in the brain. In this paper, we will introduce the details of design and sensing performance of a proto-typed microspectrometer and nanostructured probing devices for real time measurement of neurotransmitter concentrations. © 2015 SPIE.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/10940)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.