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Screening of herbal medicines from vietnam with inhibitory activity on advanced glycation end products formation (XIV)베트남 약용식물의 최종당화산물 생성저해활성 검색(XIV)
- Other Titles
- 베트남 약용식물의 최종당화산물 생성저해활성 검색(XIV)
- Authors
- Choi, S.J.; Kim, Y.S.; Kim, J.H.; The Bach, T.; Kim, J.S.
- Issue Date
- Sep-2015
- Publisher
- Korean Society of Pharmacognosy
- Keywords
- Advanced glycation end products (AGEs); Diabetic complications; Herbal medicines
- Citation
- Korean Journal of Pharmacognosy, v.46, no.3, pp.268 - 278
- Journal Title
- Korean Journal of Pharmacognosy
- Volume
- 46
- Number
- 3
- Start Page
- 268
- End Page
- 278
- ISSN
- 0253-3073
- Abstract
- In this study, 80 herbal medicines from Vietnam have been investigated with an in vitro evaluation system using advanced glycation end products (AGEs) formation inhibitory activity. Of these, 10 herbal medicines (IC50: <5 μg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, herbal medicines Strobilanthes pateriformis (aerial parts), Rhodamnia dumetorum (twigs), Glochidion rubrum (twigs), Dipterocarpus obtusifolius (twigs), Bombax ceiba (twigs), Amesiodendron chinense (twigs), Bauhinia coccinea (twigs), Lithocarpus laouanensis (twigs), Bauhinia bracteata (twigs) and Connarus paniculatus (twigs), showed more potent inhibitory activity (approximately 16-31 fold) than the positive control aminoguanidine (IC50: 76.47 μg/ml). © 2015, Korean Society of Pharmacognosy. All rights reserved.
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Related Researcher
- Kim, Joo-Hwan
- BioNano Technology (Department of Life Sciences)