Contrast-enhanced Magnetic Resonance Imaging of Brain Metastases at 7.0T versus 1.5T: A Preliminary Result
- Authors
- 백선하; 김지훈; 최성홍; 윤태진; 손영돈; 김동규; 조장희; 손철호
- Issue Date
- Mar-2015
- Publisher
- 대한자기공명의과학회
- Keywords
- Brain metastasis; Magnetic resonance imaging; 7T MRI
- Citation
- Investigative Magnetic Resonance Imaging, v.19, no.1, pp.31 - 36
- Journal Title
- Investigative Magnetic Resonance Imaging
- Volume
- 19
- Number
- 1
- Start Page
- 31
- End Page
- 36
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11700
- DOI
- 10.13104/imri.2015.19.1.31
- ISSN
- 2384-1095
- Abstract
- Purpose: To compare the depiction of brain metastases on contrast-enhanced imageswith 7.0 tesla (T) and at 1.5T MRI.
Materials and Methods: Four consecutive patients with brain metastases werescanned on 7.0T whole-body scanner and 1.5T MRI. A 3D T1-weighted gradient echosequence (3D T1-GRE) at 1.5T (voxel size = 0.9 × 0.9 × 1.5 mm3 after double-dose,gadoterate meglumine, Gd-DOTA) was compared to a 7.0T 3D T1-GRE sequence(voxel size = 0.4 × 0.4 × 0.8 mm3, single-dose Gd-DOTA) in four patients after a 5minute delay. The number of contrast-enhancing metastases in MPRAGE images wascompared in each patient by two radiologists in consensus. We measured contrastratio of enhancing brain metastases and white matter in 1.5T and 7.0T.
Results: In all four patients 7.0T 3D T1-GRE images after single-dose Gd-DOTAand 1.5T after double-dose Gd-DOTA depicted 11 brain metastases equally. In thequantitative analysis of contrast ratios of enhancing brain metastases and whitematter, the 1.5T 3D T1-GRE after double-dose showed an increased contrast ratiocompared to 7.0T 3D T1-GRE after single-dose (0.961 ± 0.571 versus 0.885 ± 0.494; n= 11 metastases). But this difference was not statistically significant (P = 0.711).
Conclusion: Our preliminary results indicate that 7.0T single-dose Gd-enhancedimages were not different to 1.5T double-dose Gd-enhanced images for the detectionof brain metastases.
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