Ultrafast sonochemical synthesis of proteininorganic nanoflowers
- Authors
- Batule, Bhagwan S.; Park, Ki Soo; Kim, Moon Il; Park, Hyun Gyu
- Issue Date
- Aug-2015
- Publisher
- DOVE MEDICAL PRESS LTD
- Keywords
- copper phosphate; laccase; epinephrine; hybrid nanomaterials
- Citation
- INTERNATIONAL JOURNAL OF NANOMEDICINE, v.10, pp.137 - 142
- Journal Title
- INTERNATIONAL JOURNAL OF NANOMEDICINE
- Volume
- 10
- Start Page
- 137
- End Page
- 142
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11869
- DOI
- 10.2147/IJN.S90274
- ISSN
- 1178-2013
- Abstract
- We developed a simple but efficient method to synthesize protein-inorganic hybrid nanostructures with a flower-like shape (nanoflowers), which relies on sonication to facilitate the synthesis of the nanoflowers. With this technique, we synthesized nanoflowers containing laccase as a model protein and copper phosphate within 5 minutes at room temperature. The resulting laccase nanoflowers yielded greatly enhanced activity, stability, and reusability, and their usefulness was successfully demonstrated by applying them in the colorimetric detection of epinephrine. The strategy developed could be used to rapidly synthesize nanoflowers for various applications in biosensor and enzyme catalysis and would expand the utilization of nanoflowers in diverse fields of biotechnology.
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Collections - 바이오나노대학 > 바이오나노학과 > 1. Journal Articles
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