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DNA hydrogel delivery vehicle for light-triggered and synergistic cancer therapy

Authors
Song, JaejungIm, KyuhyunHwang, SekyuHur, JaehyunNam, JutaekAhn, G-OneHwang, SungwooKim, SungjeePark, Nokyoung
Issue Date
2015
Publisher
ROYAL SOC CHEMISTRY
Citation
NANOSCALE, v.7, no.21, pp.9433 - 9437
Journal Title
NANOSCALE
Volume
7
Number
21
Start Page
9433
End Page
9437
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11921
DOI
10.1039/c5nr00858a
ISSN
2040-3364
Abstract
A DNA hydrogel is reported as a delivery vehicle for gold nanorods and doxorubicin. The two photothermal and chemo cancer agents were co-loaded using electrostatic and DNA binding interactions, respectively. Light-triggered and highly synergistic combination cancer therapy was demonstrated in cellular and animal models.
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Engineering (화공생명배터리공학부)
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