A nano-scale probing system with a gold nano-dot array for measurement of a single biomolecular interaction force
DC Field | Value | Language |
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dc.contributor.author | Kim, Sung Joo | - |
dc.contributor.author | Seo, Jeong Hyun | - |
dc.contributor.author | Lee, Jin Woo | - |
dc.contributor.author | Cho, Dong-Woo | - |
dc.contributor.author | Cha, Hyung Joon | - |
dc.contributor.author | Moon, Wonkyu | - |
dc.date.available | 2020-02-28T15:42:32Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2015-12 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/11991 | - |
dc.description.abstract | A new nano-scale probing system was proposed and developed to measure and analyze the interaction force between biomolecules at the single molecular level. A probing instrument adopting the working principle of atomic force microscopy (AFM) was designed to measure a single biomolecular interaction force with a patterned gold nano-dot array and functionalized AFM probe. The constructed probing system was evaluated through measurement of the unbinding force between a protein (Vibrio cholerae toxin B subunit) and a carbohydrate (GM1 pentasaccharide) as a model single biomolecular interaction. Thus, the developed probing system might be a potential platform for the effective measurement of single biomolecular level interactions. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.relation.isPartOf | RSC ADVANCES | - |
dc.title | A nano-scale probing system with a gold nano-dot array for measurement of a single biomolecular interaction force | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000366965200028 | - |
dc.identifier.doi | 10.1039/c5ra23186h | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, v.5, no.128, pp.105727 - 105730 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84951058993 | - |
dc.citation.endPage | 105730 | - |
dc.citation.startPage | 105727 | - |
dc.citation.title | RSC ADVANCES | - |
dc.citation.volume | 5 | - |
dc.citation.number | 128 | - |
dc.contributor.affiliatedAuthor | Lee, Jin Woo | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | SURFACE-PLASMON RESONANCE | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordPlus | MICROSCOPE | - |
dc.subject.keywordPlus | MOLECULES | - |
dc.subject.keywordPlus | GLYCOSYLATION | - |
dc.subject.keywordPlus | SPECIFICITY | - |
dc.subject.keywordPlus | AFFINITY | - |
dc.subject.keywordPlus | DNA | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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