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Therapeutic Potential of Human Adipose-Derived Stem Cells in Neurological Disorders

Authors
Chang, Keun-ALee, Jun-HoSuh, Yoo-Hun
Issue Date
Dec-2014
Publisher
JAPANESE PHARMACOLOGICAL SOC
Keywords
neurological disorder; adipose-derived stem cell (ASC); Alzheimer' s disease (AD); Parkinson' s disease (PD); Huntington' s disease (HD)
Citation
JOURNAL OF PHARMACOLOGICAL SCIENCES, v.126, no.4, pp.293 - 301
Journal Title
JOURNAL OF PHARMACOLOGICAL SCIENCES
Volume
126
Number
4
Start Page
293
End Page
301
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12045
DOI
10.1254/jphs.14R10CP
ISSN
1347-8613
Abstract
Stem cell therapy has been noted as a novel strategy to various diseases including neurological disorders such as Alzheimer's disease, Parkinson's disease, stroke, amyotrophic lateral sclerosis, and Huntington's disease that have no effective treatment available to date. The adipose-derived stem cells (ASCs), mesenchymal stem cells (MSCs) isolated from adipose tissue, are well known for their pluripotency with the ability to differentiate into various types of cells and immuno-modulatory property. These biological features make ASCs a promising source for regenerative cell therapy in neurological disorders. Here we discuss the recent progress of regenerative therapies in various neurological disorders utilizing ASCs.
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