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Total Synthesis of Acetylcholinesterase Inhibitor Macakurzin C

Authors
Lee, DongjooShin, IljinKo, EunjaeLee, KiyounSeo, Seung-YongKim, Hyoungsu
Issue Date
Dec-2014
Publisher
GEORG THIEME VERLAG KG
Keywords
total synthesis; natural products; aromatic Claisen rearrangement; acetylcholinesterase inhibitors; flavonoids
Citation
SYNLETT, v.25, no.19, pp.2794 - 2796
Journal Title
SYNLETT
Volume
25
Number
19
Start Page
2794
End Page
2796
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12068
DOI
10.1055/s-0034-1378904
ISSN
0936-5214
Abstract
A concise total synthesis of macakurzin C has been accomplished in nine steps (21% overall yield) from commercially available phloroglucinol, featuring a sequential aromatic Claisen rearrangement-cyclization.
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