Surface chemistry of cerium oxide nanocubes: Toxicity against pathogenic bacteria and their mechanistic study
- Authors
- Krishnamoorthy, Karthikeyan; Veerapandian, MurUgan; Zhang, Ling-He; Yun, Kyusik; Kim, Sang Jae
- Issue Date
- 25-Sep-2014
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Cerium oxide; Nanocubes; Oxygen vacancy; Surface chemistry; Anti-bacterial activity
- Citation
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.20, no.5, pp.3513 - 3517
- Journal Title
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Volume
- 20
- Number
- 5
- Start Page
- 3513
- End Page
- 3517
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12282
- DOI
- 10.1016/j.jiec.2013.12.043
- ISSN
- 1226-086X
- Abstract
- The present study investigated the bacterial toxicity of cerium oxide (CeO2) nanocubes. The X-ray diffraction and Raman spectral studies revealed the formation of nanoceria with cubic fluorite structure. The minimum inhibitory concentration (MIC) of CeO2 nanocubes against pathogenic bacteria was evaluated by a microdilution method. MICs such as 16 mu g/mL (against Escherichia coli) and 8 mu g/mL (against Salmonella typhimurium and Enterococcus faecalis), and 4 mu g/mL (against Bacillus subtilis) suggest that CeO2 nanocubes have predominant anti-bacterial activity. The evaluation of bacterial enzymatic (beta-D-galactosidase) activity in the hydrolysis of o-nitrophenol-beta-D-galactopyranoside suggested the disruption of bacterial cell wall mechanism, responsible for bacterial toxicity. (C) 2013 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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