Differences among admitting departments in alerts and alert overrides for drug - drug interaction
- Authors
- Ahn, Eun Kyoung; Kam, Hye Jin; Park, Dong Kyun; Jung, Eun Young; Lee, Youngho; Park, Rae Woong
- Issue Date
- Apr-2014
- Publisher
- WILEY
- Keywords
- drug-drug interactions; clinical decision support systems; electronic health records; pharmacoepidemiology
- Citation
- PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, v.23, no.4, pp.390 - 397
- Journal Title
- PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Volume
- 23
- Number
- 4
- Start Page
- 390
- End Page
- 397
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12757
- DOI
- 10.1002/pds.3591
- ISSN
- 1053-8569
- Abstract
- ObjectiveTo determine differences in the incidence and risk factors of alerts for drug-drug interaction (DDI) and the rate of alert overrides by an admitting department. MethodsA retrospective cohort study was performed using electronic health records of a Korean tertiary teaching hospital including all hospitalized adult patients for 18months. The main outcome measures included incidence rates of alerts for DDI and their override, hazard ratios (HRs) for DDI alerts, and odds ratios (ORs) for alert overrides by admitting department (emergency department [ED], general ward [GW], and intensive care unit [ICU]) after adjusting for other known risk factors. ResultsAmong 102379 incident admissions, 6060 had alerts for DDI (5.4/person-year). After adjusting for covariates, patients admitted to the ED (HR, 4.02; confidence interval [CI], 3.69-4.38) or ICU (HR, 1.62; CI, 1.29-2.04) showed higher risks for DDI compared with those admitted to the GW. The alert-override rate was significantly higher in the ED (OR 1.68) than in the GW; however, there was no significant difference between GW and ICU. The prevalence of DDI alerts and their override rate were also demonstrated. DiscussionThe incidence of DDI and the alert-override rate differed by admitting department. The ED and ICU were associated with higher risks for alerts on DDI than did the GW after adjusting for other known risk factors. ConclusionsAdmitting department was an independent risk factor for alerts and alert overrides. Strategies to reduce alerts and alert overrides should consider the admitting department. Copyright (c) 2014 John Wiley & Sons, Ltd.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - IT융합대학 > 컴퓨터공학과 > 1. Journal Articles
- 의과대학 > 의학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12757)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.