Distinct Mechanisms of DNA Sensing Based on N-Doped Carbon Nanotubes with Enhanced Conductance and Chemical Selectivity
- Authors
- Kim, Han Seul; Lee, Seung Jin; Kim, Yong-Hoon
- Issue Date
- Feb-2014
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- DNA sequencing; molecular sensing; carbon nanotube; electron tunneling; first-principles calculations
- Citation
- SMALL, v.10, no.4, pp.774 - 781
- Journal Title
- SMALL
- Volume
- 10
- Number
- 4
- Start Page
- 774
- End Page
- 781
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12846
- DOI
- 10.1002/smll.201301225
- ISSN
- 1613-6810
- Abstract
- N-doped capped carbon nanotube (CNT) electrodes applied to DNA sequencing are studied by first-principles calculations. For the face-on nucleobase junction configurations, a conventional conductance ordering is obtained where the largest signal results from guanine according to its high highest occupied molecular orbital (HOMO) level, whereas for the edge-on counterparts a distinct conductance ordering is observed where the low-HOMO thymine provides the largest signal. The edge-on mode is shown to operate based on a novel molecular sensing mechanism that reflects the chemical connectivity between N-doped CNT caps that can act both as electron donors and electron acceptors and DNA functional groups that include the hyperconjugated thymine methyl group.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/12846)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.