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Screening of Korean herbal medicines with inhibitory effect on aldose reductase (IX)한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(IX)
- Other Titles
- 한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(IX)
- Authors
- Choi, S.-J.; Kim, Y.S.; Kim, J.H.; Kim, J.S.
- Issue Date
- Dec-2014
- Publisher
- Korean Society of Pharmacognosy
- Keywords
- Aldose reductase inhibitor; Diabetic complications; Korean herbal medicines
- Citation
- Korean Journal of Pharmacognosy, v.45, no.4, pp.354 - 358
- Journal Title
- Korean Journal of Pharmacognosy
- Volume
- 45
- Number
- 4
- Start Page
- 354
- End Page
- 358
- ISSN
- 0253-3073
- Abstract
- Aldose reductase (AR) has been demonstrated to play important role in the development of the diabetic complications such as diabetic retinopathy, diabetic neuropathy and diabetic nephropathy. To discover novel treatments for diabetic complications from natural sources, 69 Korean herbal medicines have been investigated for inhibitory activities on AR. Among them, 7 herbal medicines, Eleutherococcus sessiliflorus (stems), Artemisia japonica (whole plants), Wisteria floribunda (leaves), Eurya japonica (stems, twigs and leaves, leaves), Ampelopsis brevipedunculata (stems) exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid as positive control. © 2015, Korean Society of Pharmacognosy. All rights reserved.
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Related Researcher
- Kim, Joo-Hwan
- BioNano Technology (Department of Life Sciences)