최근 10년간의 水蛭 연구 동향: 비만 및 대사증후군에의 응용 가능성제고

Abstract

Objectives: The purpose of this study is to analyse research trends about medical leech in the last10 years. Methods: We searched the papers with key words of ‘medical leech’, ‘水蛭’ in China KnowledgeResource Integrated Database (CNKI), Korean traditional knowledge portal, DBPIA, KISS. Weclassified the papers by year and content. Results: 1. Result of the classification on the basis of the research methods, 50 studies are clinicalcase reports, 301 studies are experimental paper, 599 studies are clinical trial study, 219 studiesare literature review. 2. Result of the classification on the basis of the research topics, 454 studiesare the effect of anticoagulant research, 84 studies are diabetes and renal disease research, 194studies are pharmacological properties research, and 43 studies are effect of allergic andanti-inflammatory research. 3. The proportion of the coagulation effect study tends to decreaseevery year since 2006. 4. Leech research tends to decrease in last 3 years. 5. Recently, there aremany research in psychiatry, orthopedic diseases and beauty. 6. There are 10 studies related toleech in Korean. Conclusions: The researches of medical leech are actively done. The diversity of subjects isgetting wider and richer.