동종이식으로 치료한 급성 골수성 백혈병 항암 치료 후골수 무형성증 1예Acute Myeloid Leukemia with Persistent Marrow Aplasia after Chemotherapy Treated with Reduced-Intensity Allogeneic Stem Cell Transplantation
- Other Titles
- Acute Myeloid Leukemia with Persistent Marrow Aplasia after Chemotherapy Treated with Reduced-Intensity Allogeneic Stem Cell Transplantation
- Authors
- 윤현화; 홍준식; 김수영; 이동민; 박진희; 안정열; 이재훈
- Issue Date
- Feb-2014
- Publisher
- 대한내과학회
- Keywords
- 급성 골수성 백혈병; 조혈모세포이식; 무형성빈혈; 호중구 감소증; 항암화학요법; Acute myeloid leukemia; Stem cell transplantation; Aplastic anemia; Neutropenia; Chemotherapy
- Citation
- 대한내과학회지, v.86, no.2, pp.242 - 246
- Journal Title
- 대한내과학회지
- Volume
- 86
- Number
- 2
- Start Page
- 242
- End Page
- 246
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/13817
- DOI
- 10.3904/kjm.2014.86.2.242
- ISSN
- 1738-9364
- Abstract
- Persistent bone marrow aplasia after intensive chemotherapy is uncommon, but is one of the fatal complications in patients withacute myeloid leukemia (AML). Although allogeneic hematopoietic stem cell transplantation (HSCT) is considered to becontraindicated for patients who have hematologic diseases with serious infections, such as bacterial septicemia or invasive fungaldiseases, combined with prolonged neutropenia due to frequent morbidity and mortality, such risks can be overcome bynon-myeloablative conditioning and best supportive care. Here, we report an AML patient with persistent marrow aplasia afterinduction therapy, treated successfully with reduced-intensity allogeneic HSCT despite severe bacterial and fungal infections.
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