수액치료 전략이 초극소 저체중 출생아의 비핍뇨성 고칼륨혈증에 미치는 영향The Impact of Fluid Therapy Strategies on Nonoliguric Hyperkalemia in Extremely Low Birth Weight Infants
- Other Titles
- The Impact of Fluid Therapy Strategies on Nonoliguric Hyperkalemia in Extremely Low Birth Weight Infants
- Authors
- 김민영; 장은재; 김영혜; 장우정; 조혜정; 이지성; 손동우
- Issue Date
- 2014
- Publisher
- 대한신생아학회
- Keywords
- Amino acids/administration and dosage; Calcium/therapeutic use; Hyperkalemia/prevention and control; Infant/extremely low birth weight; Nitrogen/administration and dosage; Phosphorus/blood; Potassium/blood
- Citation
- Neonatal medicine, v.21, no.1, pp.28 - 37
- Journal Title
- Neonatal medicine
- Volume
- 21
- Number
- 1
- Start Page
- 28
- End Page
- 37
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/13826
- ISSN
- 2287-9412
- Abstract
- Purpose: The aim of this study was to characterize the changes in the incidence and clinical characteristics of nonoliguric hyperkalemia (NOHK), together with plasma potassium levels, according to the fluid therapy strategies for extremely low birth weight infants (ELBWIs) during the first few days of life.
Methods: This retrospective study enrolled ELBWIs. We analyzed the occurrence of NOHK, plasma potassium levels, other biochemical data, and fluid balances according to historically controlled strategies such as conventional limited-volume supply and low-dose calcium supplementation (P1), increased-volume supply and high-dose calcium supplementation (P2), and early aggressive nutrition (EAN) and high-dose calcium supplementation (P3).
Results: The incidence of NOHK and the plasma potassium levels in P2 (127 ELBWIs) were not different from those in P1 (39 ELBWIs). However, arrhythmia and fatality significantly decreased in P2 compared to those in P1. In P3 (68 ELBWIs), the incidence of NOHK after 24 h and the plasma potassium levels after 36 h of life were significantly reduced compared to those in P1 and P2. Neither arrhythmia nor fatality developed in P3.
Conclusion: EAN combined with high-dose calcium supplementation could be a potential strategy for the prevention of NOHK along with consequent arrhythmia and fatality in ELBWIs.
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