A study of Gd loaded silica nanoparticles for both optical and magnetic resonance imaging of cells
DC Field | Value | Language |
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dc.contributor.author | Lee, Haisung | - |
dc.contributor.author | Yi, Dong Kee | - |
dc.date.available | 2020-02-28T23:45:22Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-06-01 | - |
dc.identifier.issn | 0167-577X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14487 | - |
dc.description.abstract | We have developed fluorescent nanoparticle-based T-1 contrast enhancing magnetic resonance imaging (MRI) agents, for the purpose of dual imaging in vivo. Gd(III) chelated silica nanoparticles were successfully synthesized with dual-mode diagnostics feasibility in MRI and fluorescence imaging analysis. Gd-chelated silica nanoparticles were studied, which were formed via polyelectrolyte encapping methods. A 9.4T micro-image instrument was used to investigate the T-1 contrast enhancement effects of the Gd-chelated silica nanoparticles. The resulting Gd chelated nanoparticles were used in cell tracking and bio-distribution experiments with dual mode imaging of A549 lung cancer cells and mouse models. These Gd-silica nanoparticles are promising dual mode materials, functioning as T-1 MRI contrast agents and organ specific contrast agents. (C) 2013 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.relation.isPartOf | MATERIALS LETTERS | - |
dc.subject | CONTRAST AGENTS | - |
dc.subject | MRI | - |
dc.title | A study of Gd loaded silica nanoparticles for both optical and magnetic resonance imaging of cells | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000320079400027 | - |
dc.identifier.doi | 10.1016/j.matlet.2013.03.016 | - |
dc.identifier.bibliographicCitation | MATERIALS LETTERS, v.100, pp.98 - 101 | - |
dc.identifier.scopusid | 2-s2.0-84875732558 | - |
dc.citation.endPage | 101 | - |
dc.citation.startPage | 98 | - |
dc.citation.title | MATERIALS LETTERS | - |
dc.citation.volume | 100 | - |
dc.contributor.affiliatedAuthor | Yi, Dong Kee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Gd ion | - |
dc.subject.keywordAuthor | Dual imaging | - |
dc.subject.keywordAuthor | Colloid | - |
dc.subject.keywordAuthor | MRI agent | - |
dc.subject.keywordAuthor | Hybrid | - |
dc.subject.keywordPlus | CONTRAST AGENTS | - |
dc.subject.keywordPlus | MRI | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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