Origin of B-0 orientation dependent R*(2) (=1/T*(2)) in white matter
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, Se-Hong | - |
dc.contributor.author | Kim, Young-Bo | - |
dc.contributor.author | Cho, Zang-Hee | - |
dc.contributor.author | Lee, Jongho | - |
dc.date.available | 2020-02-28T23:45:27Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2013-06 | - |
dc.identifier.issn | 1053-8119 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14489 | - |
dc.description.abstract | Recent MRI studies have demonstrated that the relative orientation of white matter fibers to the B-0 field significantly affects R*(2) measurement. In this work, the origin of this effect was investigated by measuring R-2 and R*(2) in multiple orientations and fitting the results to magnetic susceptibility-based models and magic angle-based models. To further explore the source of magnetic susceptibility effect, the contribution of tissue iron to the orientation dependent R*(2) contrast was investigated. Additionally, the effects of temperature on R*(2) and orientation dependent R*(2) contrasts were studied to understand the differences reported between a fixed specimen at room temperature and in vivo at body temperature. The results suggest that the B-0 dependent R*(2) variation is better explained by the magnetic susceptibility-based model with susceptibility anisotropy. However, extracting tissue iron did not reduce the orientation dependent R*(2) contrast, suggesting iron is not the origin of the contrast. This leaves susceptibility effects from myelin as the most probable origin of the contrast. Temperature showed large contribution on both R*(2) and orientation dependent R*(2) contrasts, explaining a portion of the contrast difference between the in-vivo and in-vitro conditions. (C) 2013 Elsevier Inc. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.relation.isPartOf | NEUROIMAGE | - |
dc.subject | MYELIN WATER FRACTION | - |
dc.subject | HIGH-FIELD MRI | - |
dc.subject | IN-VIVO | - |
dc.subject | MAGNETIC-RESONANCE | - |
dc.subject | HUMAN BRAIN | - |
dc.subject | PHASE-CONTRAST | - |
dc.subject | FIBER ORIENTATION | - |
dc.subject | RELAXATION | - |
dc.subject | IRON | - |
dc.subject | MYELOARCHITECTURE | - |
dc.title | Origin of B-0 orientation dependent R*(2) (=1/T*(2)) in white matter | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000317084500008 | - |
dc.identifier.doi | 10.1016/j.neuroimage.2013.01.051 | - |
dc.identifier.bibliographicCitation | NEUROIMAGE, v.73, pp.71 - 79 | - |
dc.identifier.scopusid | 2-s2.0-84874390579 | - |
dc.citation.endPage | 79 | - |
dc.citation.startPage | 71 | - |
dc.citation.title | NEUROIMAGE | - |
dc.citation.volume | 73 | - |
dc.contributor.affiliatedAuthor | Kim, Young-Bo | - |
dc.contributor.affiliatedAuthor | Cho, Zang-Hee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Magnetic susceptibility anisotropy | - |
dc.subject.keywordAuthor | Magic angle effects | - |
dc.subject.keywordAuthor | B-0 orientation dependent transverse magnetization (T-2 and T*(2)) | - |
dc.subject.keywordAuthor | MRI relaxometry | - |
dc.subject.keywordPlus | MYELIN WATER FRACTION | - |
dc.subject.keywordPlus | HIGH-FIELD MRI | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | MAGNETIC-RESONANCE | - |
dc.subject.keywordPlus | HUMAN BRAIN | - |
dc.subject.keywordPlus | PHASE-CONTRAST | - |
dc.subject.keywordPlus | FIBER ORIENTATION | - |
dc.subject.keywordPlus | RELAXATION | - |
dc.subject.keywordPlus | IRON | - |
dc.subject.keywordPlus | MYELOARCHITECTURE | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Neuroimaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.