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Electrical Impedance Characterization of Adipose Tissue-Derived Stem Cells Cultured on Indium Tin Oxide Electrodes

Authors
Jun, Hee-SookChoi, WoohyukKim, Jae YoungCho, Sungbo
Issue Date
Apr-2013
Publisher
AMER SCIENTIFIC PUBLISHERS
Keywords
Cell-Electrode Interface; Impedance Spectroscopy; Parylene; Stem Cells; Transparent Electrode
Citation
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, v.9, no.4, pp.699 - 702
Journal Title
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume
9
Number
4
Start Page
699
End Page
702
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14632
DOI
10.1166/jbn.2013.1529
ISSN
1550-7033
Abstract
The optical and electrical analysis of the stem cell growth and differentiation using the transparent electrode can be applied to develop new treatment strategies based on stem cell tissue engineering or therapy. In this article, it was investigated whether adipose tissue-derived stem cells (ADSCs) can be cultured on the indium tin oxide electrodes (ITO) and whether the cell growth can be characterized by impedance spectroscopy. From phase contrast microscopy of ADSCs, it was observed that ADSCs adhered and spread on the surface of ITO electrode during cell growth. The measured electrical impedance spectra of the cell-covered electrode were characterized by an equivalent circuit model. By fitting analysis, the resistance and capacitance of ADSCs were extrapolated. The degree of cell coverage on the electrode during cell growth was sensitively detected by monitoring the impedance magnitude.
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IT융합대학 > 전자공학과 > 1. Journal Articles
바이오나노대학 > 생명과학과 > 1. Journal Articles
약학대학 > 약학과 > 1. Journal Articles

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BioNano Technology (Department of Life Sciences)
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