Polymer microneedles for transdermal drug delivery
- Authors
- Lee, Jeong Woo; Han, Mee-Ree; Park, Jung-Hwan
- Issue Date
- Apr-2013
- Publisher
- TAYLOR & FRANCIS LTD
- Keywords
- Microneedle; polymer; biodegradable; dissolving; transdermal drug delivery; microfabrication
- Citation
- JOURNAL OF DRUG TARGETING, v.21, no.3, pp.211 - 223
- Journal Title
- JOURNAL OF DRUG TARGETING
- Volume
- 21
- Number
- 3
- Start Page
- 211
- End Page
- 223
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14654
- DOI
- 10.3109/1061186X.2012.741136
- ISSN
- 1061-186X
- Abstract
- A microneedle system has been developed to deliver chemical and biological agents through the stratum corneum, which is the main barrier to drug delivery. Recently, microneedles have been fabricated from various kinds of polymers, including biocompatible polymer, biodegradable polymer, and water-soluble polymer. Polymer microneedles offer the benefits of ease of fabrication, cost-effectiveness, and mass production, as well as controlled drug release using the water solubility and degradation properties of polymer. In this review, the key features of polymer microneedles are discussed, including fabrication, materials, mechanical properties, drug delivery properties, and applications. Polymer microneedles provide a promising method for transdermal drug delivery by utilizing various physical and chemical properties of polymer.
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Collections - 바이오나노대학 > 바이오나노학과 > 1. Journal Articles
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