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Screening of Korean herbal medicines with inhibitory effect on Aldose reductase (VIII)
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Y.M. | - |
| dc.contributor.author | Kim, Y.S. | - |
| dc.contributor.author | Kim, J.H. | - |
| dc.contributor.author | Kim, J.S. | - |
| dc.date.available | 2020-02-29T00:46:48Z | - |
| dc.date.created | 2020-02-12 | - |
| dc.date.issued | 2013-06 | - |
| dc.identifier.issn | 0253-3073 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14869 | - |
| dc.description.abstract | Aldose reductase (AR) plays a central role in the development of the diabetic complications. Eighty one Korean herbal medicines have been investigated for inhibitory activities on AR. Among them, fourteen herbal medicines exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid (TMG) as positive control. Particularly, Xanthium strumarium (fruit, whole plant), Ilex cornuta (stem and leaf), Vitex rotundifolia(stem), Sophora flavescens (whole plant), Platycarya stobilacea (flower) showed two times more potent inhibitory activity than 3,3-tetramethyleneglutaric acid (TMG). | - |
| dc.language | 한국어 | - |
| dc.language.iso | ko | - |
| dc.publisher | 한국생약학회 | - |
| dc.relation.isPartOf | Korean Journal of Pharmacognosy | - |
| dc.title | Screening of Korean herbal medicines with inhibitory effect on Aldose reductase (VIII) | - |
| dc.title.alternative | 한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VIII) | - |
| dc.type | Article | - |
| dc.type.rims | ART | - |
| dc.description.journalClass | 1 | - |
| dc.identifier.bibliographicCitation | Korean Journal of Pharmacognosy, v.44, no.2, pp.168 - 175 | - |
| dc.identifier.kciid | ART001778021 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.scopusid | 2-s2.0-84926644821 | - |
| dc.citation.endPage | 175 | - |
| dc.citation.startPage | 168 | - |
| dc.citation.title | Korean Journal of Pharmacognosy | - |
| dc.citation.volume | 44 | - |
| dc.citation.number | 2 | - |
| dc.contributor.affiliatedAuthor | Kim, J.H. | - |
| dc.type.docType | Article | - |
| dc.subject.keywordAuthor | Aldose reductase inhibitor | - |
| dc.subject.keywordAuthor | Diabetic complications | - |
| dc.subject.keywordAuthor | Korean herbal medicines | - |
| dc.subject.keywordPlus | aldehyde reductase | - |
| dc.subject.keywordPlus | Ilex cornuta extract | - |
| dc.subject.keywordPlus | plant extract | - |
| dc.subject.keywordPlus | Platycarya stobilacea extract | - |
| dc.subject.keywordPlus | Sophora flavescens extract | - |
| dc.subject.keywordPlus | tetramethyleneglutaric acid | - |
| dc.subject.keywordPlus | unclassified drug | - |
| dc.subject.keywordPlus | Vitex rotundifolia extract | - |
| dc.subject.keywordPlus | xanthium strumarium extract | - |
| dc.subject.keywordPlus | article | - |
| dc.subject.keywordPlus | controlled study | - |
| dc.subject.keywordPlus | diabetes mellitus | - |
| dc.subject.keywordPlus | enzyme inhibition | - |
| dc.subject.keywordPlus | herbal medicine | - |
| dc.subject.keywordPlus | Ilex | - |
| dc.subject.keywordPlus | latycarya stobilacea | - |
| dc.subject.keywordPlus | medicinal plant | - |
| dc.subject.keywordPlus | nonhuman | - |
| dc.subject.keywordPlus | Platycarya stobilacea | - |
| dc.subject.keywordPlus | screening | - |
| dc.subject.keywordPlus | Sophora flavescens | - |
| dc.subject.keywordPlus | Vitex rotundifolia | - |
| dc.subject.keywordPlus | Xanthium | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
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Related Researcher
- Kim, Joo-Hwan
- BioNano Technology (Department of Life Sciences)