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Screening of Korean herbal medicines with inhibitory effect on Aldose reductase (VIII)한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VIII)
- Other Titles
- 한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VIII)
- Issue Date
- Jun-2013
- Publisher
- 한국생약학회
- Keywords
- Aldose reductase inhibitor; Diabetic complications; Korean herbal medicines
- Citation
- Korean Journal of Pharmacognosy, v.44, no.2, pp.168 - 175
- Journal Title
- Korean Journal of Pharmacognosy
- Volume
- 44
- Number
- 2
- Start Page
- 168
- End Page
- 175
- ISSN
- 0253-3073
- Abstract
- Aldose reductase (AR) plays a central role in the development of the diabetic complications. Eighty one Korean herbal medicines have been investigated for inhibitory activities on AR. Among them, fourteen herbal medicines exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid (TMG) as positive control. Particularly, Xanthium strumarium (fruit, whole plant), Ilex cornuta (stem and leaf), Vitex rotundifolia(stem), Sophora flavescens (whole plant), Platycarya stobilacea (flower) showed two times more potent inhibitory activity than 3,3-tetramethyleneglutaric acid (TMG).
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Collections - 바이오나노대학 > 생명과학과 > 1. Journal Articles
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Related Researcher
- Kim, Joo-Hwan
- BioNano Technology (Department of Life Sciences)