Screening of herbal medicines from China with inhibitory activity on advanced glycation end products (AGEs) formation (X)
DC Field | Value | Language |
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dc.contributor.author | Kim, Y.S. | - |
dc.contributor.author | Lee, Y.M. | - |
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Kim, J.S. | - |
dc.date.available | 2020-02-29T00:46:52Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2013-09 | - |
dc.identifier.issn | 0253-3073 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14873 | - |
dc.description.abstract | Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 54 herbal medicines from China have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 6 herbal medicines (IC<inf>50</inf><5 μg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, herbal medicines Punica granatum (peels), Terminalia chebula (fruits), Rheum palmatum (roots), Oxyria digyna (stems and leaves), Anisodus luridus (roots) and Quercus schottkyana(stems and leaves) showed more potent inhibitory activity (approximately 9-43 fold) than the positive control aminoguanidine (IC<inf>50</inf>=77.04 μg/ml). | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 한국생약학회 | - |
dc.relation.isPartOf | Korean Journal of Pharmacognosy | - |
dc.title | Screening of herbal medicines from China with inhibitory activity on advanced glycation end products (AGEs) formation (X) | - |
dc.title.alternative | 중국 약용식물의 최종당화산물 생성저해활성 검색 (X) | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pharmacognosy, v.44, no.3, pp.305 - 311 | - |
dc.identifier.kciid | ART001804338 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84940325784 | - |
dc.citation.endPage | 311 | - |
dc.citation.startPage | 305 | - |
dc.citation.title | Korean Journal of Pharmacognosy | - |
dc.citation.volume | 44 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Kim, J.H. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Advanced glycation end products (AGEs) | - |
dc.subject.keywordAuthor | Chinese herbal medicines | - |
dc.subject.keywordAuthor | Diabetic complications | - |
dc.subject.keywordPlus | advanced glycation end product | - |
dc.subject.keywordPlus | aminoguanidine | - |
dc.subject.keywordPlus | Anisodus luridus extarct | - |
dc.subject.keywordPlus | Oxyria digyna extract | - |
dc.subject.keywordPlus | plant extract | - |
dc.subject.keywordPlus | pomegranate extract | - |
dc.subject.keywordPlus | Quercus schottkyana extarct | - |
dc.subject.keywordPlus | rhubarb extract | - |
dc.subject.keywordPlus | Terminalia chebula extract | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | biological activity | - |
dc.subject.keywordPlus | herbal medicine | - |
dc.subject.keywordPlus | IC 50 | - |
dc.subject.keywordPlus | in vitro study | - |
dc.subject.keywordPlus | inhibitory activity | - |
dc.subject.keywordPlus | nonhuman | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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