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Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate

Authors
Park, Jin SunJung, Eul SikChoi, WoosukPark, Soo YongRim, Min YoungYu, InkuPark, HyeonsuLee, Sang MinPark, Jeong-WoongJeong, Sung HwanLee, Sang PyoPark, Sanghui
Issue Date
Jul-2013
Publisher
대한결핵및호흡기학회
Keywords
Arthiritis, rheumatoid; Bronchial diseases; Methotrexate; Nontuberculous mycobacteria; Tuberculosis, pulmonary
Citation
Tuberculosis and Respiratory Diseases, v.75, no.1, pp.28 - 31
Journal Title
Tuberculosis and Respiratory Diseases
Volume
75
Number
1
Start Page
28
End Page
31
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14929
DOI
10.4046/trd.2013.75.1.28
ISSN
1738-3536
Abstract
Methotrexate (MTX) has been established as a standard disease-modifying anti-rheumatic drug. If adequate disease control is achieved for a reasonable period of time, tapering the MTX dosage is recommended because the chronic use of MTX can result in opportunistic infection. We present here a case of a woman with rheumatoid arthritis taking MTX, and the woman developed actively caseating endobronchial Mycobacterium intracellulare disease with pulmonary infiltrations. After discontinuing the MTX, the patient was able to tolerate 18 months of antimycobacterial treatment without flare ups of rheumatoid arthritis, and she completely recovered from nontuberculous mycobacterial respiratory disease. Copyright © 2013 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.
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