Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate
- Authors
- Park, Jin Sun; Jung, Eul Sik; Choi, Woosuk; Park, Soo Yong; Rim, Min Young; Yu, Inku; Park, Hyeonsu; Lee, Sang Min; Park, Jeong-Woong; Jeong, Sung Hwan; Lee, Sang Pyo; Park, Sanghui
- Issue Date
- Jul-2013
- Publisher
- 대한결핵및호흡기학회
- Keywords
- Arthiritis, rheumatoid; Bronchial diseases; Methotrexate; Nontuberculous mycobacteria; Tuberculosis, pulmonary
- Citation
- Tuberculosis and Respiratory Diseases, v.75, no.1, pp.28 - 31
- Journal Title
- Tuberculosis and Respiratory Diseases
- Volume
- 75
- Number
- 1
- Start Page
- 28
- End Page
- 31
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/14929
- DOI
- 10.4046/trd.2013.75.1.28
- ISSN
- 1738-3536
- Abstract
- Methotrexate (MTX) has been established as a standard disease-modifying anti-rheumatic drug. If adequate disease control is achieved for a reasonable period of time, tapering the MTX dosage is recommended because the chronic use of MTX can result in opportunistic infection. We present here a case of a woman with rheumatoid arthritis taking MTX, and the woman developed actively caseating endobronchial Mycobacterium intracellulare disease with pulmonary infiltrations. After discontinuing the MTX, the patient was able to tolerate 18 months of antimycobacterial treatment without flare ups of rheumatoid arthritis, and she completely recovered from nontuberculous mycobacterial respiratory disease. Copyright © 2013 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.
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