Glucosamine functionalized copper nanoparticles: Preparation, characterization and enhancement of anti-bacterial activity by ultraviolet irradiation
- Authors
- Veerapandian, Murugan; Sadhasivam, Sathya; Choi, Joonho; Yun, Kyusik
- Issue Date
- 15-Oct-2012
- Publisher
- ELSEVIER SCIENCE SA
- Keywords
- Glucosamine functionalization; Copper nanoparticles; UV irradiation; Anti-bacterial effect
- Citation
- CHEMICAL ENGINEERING JOURNAL, v.209, pp.558 - 567
- Journal Title
- CHEMICAL ENGINEERING JOURNAL
- Volume
- 209
- Start Page
- 558
- End Page
- 567
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16084
- DOI
- 10.1016/j.cej.2012.08.054
- ISSN
- 1385-8947
- Abstract
- Glucosamine functionalized copper nanoparticles (GlcN-Cu NPs) were synthesized for anti-bacterial function. Electron microscopic characterization revealed the hybrid morphology, selected-area electron diffraction pattern and elemental mapping of GlcN-Cu NPs. Average particle size distribution was 93 8 nm. GlcN functionalization allowed significant shift in the ultraviolet (UV)-visible absorbance at 525 nm and fluorescent emission wavelength at approximately 353 nm for Cu NPs. Stretching and bending vibrations from Fourier transform-infrared and Raman analysis ensured GlcN functionalization on Cu NPs. We demonstrated the enhanced anti-bacterial property of GlcN-Cu NPs against two Gram-negative and Gram-positive bacterial strains by UV irradiation of prepared materials for 10 and 20 min. Minimum inhibitory concentration (MIC) determinations revealed that UV irradiated GlcN-Cu NPs possessed enhanced anti-bacterial activity than simple Cu NPs, Cu metal salt and standard anti-biotic kanamycin. MIC for GlcN-Cu NPs was 4 mu g/mL for Escherichia coli and 8 mg/mL for Salmonella typhimurium, Enterococcus faecalis and Bacillus subtilis, confirming its potential as an anti-infective agent for the protection of medical instruments, water treatment and in food processing. Crown Copyright (C) 2012 Published by Elsevier B.V. All rights reserved.
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