Improvement of mechanical properties and blood compatibility of PLLA nanocomposites by incorporation of polyhedral oligomeric silsesquioxane
- Authors
- Bach, Quang Vu; Choi, Jiyeon; Joung, Yoon Ki; Park, Bang Ju; Han, Dong Keun
- Issue Date
- Sep-2012
- Publisher
- POLYMER SOC KOREA
- Keywords
- PLLA; POSS; nanocomposite; mechanical property; blood compatibility
- Citation
- MACROMOLECULAR RESEARCH, v.20, no.9, pp.996 - 1001
- Journal Title
- MACROMOLECULAR RESEARCH
- Volume
- 20
- Number
- 9
- Start Page
- 996
- End Page
- 1001
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/16208
- DOI
- 10.1007/s13233-012-0196-x
- ISSN
- 1598-5032
- Abstract
- A series of hybrid nanocomposites containing poly(L-lactide) (PLLA) and polyhedral oligomeric silsesquioxane (POSS) was prepared by solvent casting method for the enhancement of the mechanical properties of PLLA. One of them was mixed by only a physical blending between PLLA and POSS to form PLLA/POSS nanocomposite that did not show considerable improvement. In the other hand, two types of PLLA-POSS additives were synthesized via the ring-opening polymerization of L-lactide in the presence of POSS in different content. On these additives, POSS played as not only an initiator for the ring-opening polymerization reaction due to its hydroxyl functional groups on the surface but also a type of hybrid filler for PLLA/PLLA-POSS nanocomposite after mixing with PLLA matrix. PLLA/PLLA-POSS composite showed significant improvement in mechanical properties because of covalent bonding between PLLA and POSS. In particular, the tensile modulus has been apparently increased in PLLA/5PLLA-5POSS nanocomposites (1,449 MPa) with respect to PLLA control (498 MPa). SEM and XRD data indicated that the dispersion of PLLA-modified POSS was better than that of POSS in PLLA matrix. Although the contact angle was not significantly different, the protein adsorption and platelet adhesion are reduced slightly in PLLA/PLLA-POSS nanocomposite as compared to those of PLLA control and PLLA/POSS. Therefore, it is expected that biodegradable POSS nanocomposite may be helpful to be utilized in biomedical devices such as drug-eluting stents and artificial implants.
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