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An anesthetic experience of a patient with paraneoplastic encephalitis -A case report-

Authors
이미금곽현정김홍순정월선양미란
Issue Date
2012
Publisher
대한마취통증의학회
Keywords
General anesthesia; Mature teratoma; Paraneoplastic syndromes.
Citation
Anesthesia and Pain Medicine, v.7, no.1, pp.63 - 66
Journal Title
Anesthesia and Pain Medicine
Volume
7
Number
1
Start Page
63
End Page
66
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17260
ISSN
1975-5171
Abstract
Paraneoplastic encephalitis associated with an ovarian teratoma has been related to the development of antibodies to specific heteromers of the N-methyl-D-aspartate receptor (NMDAR). The disorder, known as anti-NMDAR encephalitis, is characterized by psychiatric symptoms, seizures, mood and behavioral changes as well as involuntary movement. Since the NMDAR is the target of many anesthetic drugs, the presence of anti-NMDAR antibodies might influence the requirements of anesthetics or their effects. We report the presentation and anesthetic experience of a young patient with anti-NMDAR encephalitis undergoing surgical excision of two ovarian teratomas, and we also review the relevant literature.
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