나노기공 표면에서의 세포 행동양식에 관한 연구Investigation of Cell Behavior on Nanoporous Surface
- Other Titles
- Investigation of Cell Behavior on Nanoporous Surface
- Authors
- 정성희; 윤원중; 민준홍
- Issue Date
- 2012
- Publisher
- 한국생물공학회
- Keywords
- AAO (Anodic Aluminum Oxide); Nanostructure; cell behavior; SEM; protein adsorption
- Citation
- KSBB Journal, v.27, no.1, pp.45 - 50
- Journal Title
- KSBB Journal
- Volume
- 27
- Number
- 1
- Start Page
- 45
- End Page
- 50
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17326
- ISSN
- 1225-7117
- Abstract
- In this paper, we investigated the effect of nanostructure on the cell behaviors such as adhesion and growth rate. Nanoporous structures with various diameters (30, 40, 45, 50, 60 nm) and 500 nm of the depth were fabricated using the anodizing method. The water contact angle of the surface consisting of nanopores with 30 nm diameter was 40 degree and those were 60~70 degree in cases of nanopores with over 40 nm diameter. Hela cells were cultivated on various nanoporous structure surface to investigate the cell behavior on nanostructure. As a result,Hela cells preferred 30 nm diameter nanoporous surface that has lower water contact angle. This result was confirmed by protein adsorption experiment and scanning electron microscope investigation.
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Collections - 공과대학 > 화공생명공학과 > 1. Journal Articles
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