어성초(魚腥草)의 면역활성에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김정현 | - |
dc.contributor.author | 김윤상 | - |
dc.contributor.author | 임은미 | - |
dc.date.available | 2020-02-29T09:42:00Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1229-4292 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17345 | - |
dc.description.abstract | Objectives: The aim of this study is to investigate immune enhancing effect of Houttuyniae Herba water extract(HW) on RAW 264.7 cell of mouse macrophages. Methods: Effects of HW on productions of nitric oxide(NO) and hydrogen peroxide(H2O2) in RAW 264.7 mouse macrophages were measured. Effect of HW on production of cytokines such as interleukin(IL)-1β, IL-6, and tumor necrosis factor(TNF)-α in RAW 264.7 cells was accessed by a multiplex bead array assay based on xMAP technology. All of results were represented P<0.05 compared to the normal. Results:1. After 24 hr incubation, HW increased significantly NO production in RAW 264.7 cells at the concentrations of 25, 50, 100 and 200 ㎍/mL. 2. After 24 hr incubation, HW increased significantly hydrogen peroxide production in RAW 264.7 cells at the concentrations of 25, 50, 100 and 200 ㎍/mL. 3. After 24 hr incubation, HW increased significantly IL-1β production in RAW 264.7 cells at the concentrations of 100 and 200 ㎍/mL. 4. After 24 hr incubation, HW increased significantly IL-6 production in RAW 264.7 cells at the concentrations of 100 and 200 ㎍/mL. 5. After 24 hr incubation, HW increased significantly TNF-α production in RAW 264.7 cells at the concentrations of 50, 100, and 200 ㎍/mL. Conclusions: These results suggest that HW has immune enhancing activity related with its increasement of NO, hydrogen peroxide, IL-1β, IL-6, and TNF-α in macrophages. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한한방부인과학회 | - |
dc.relation.isPartOf | 대한한방부인과학회지 | - |
dc.title | 어성초(魚腥草)의 면역활성에 미치는 영향 | - |
dc.title.alternative | Immune Enhancing Effect of Houttuyniae Herba on Mouse Macrophage | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 대한한방부인과학회지, v.25, no.2, pp.12 - 22 | - |
dc.identifier.kciid | ART001662088 | - |
dc.citation.endPage | 22 | - |
dc.citation.startPage | 12 | - |
dc.citation.title | 대한한방부인과학회지 | - |
dc.citation.volume | 25 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 김정현 | - |
dc.contributor.affiliatedAuthor | 김윤상 | - |
dc.contributor.affiliatedAuthor | 임은미 | - |
dc.subject.keywordAuthor | Houttuyniae Herba | - |
dc.subject.keywordAuthor | macrophage | - |
dc.subject.keywordAuthor | cytokine | - |
dc.subject.keywordAuthor | hydrogen peroxide | - |
dc.subject.keywordAuthor | NO | - |
dc.description.journalRegisteredClass | kci | - |
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