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A case of therapy-related acute myeloid leukemia with inv(16)(p13.1q22) after single low-dose iodine-131 treatment for thyroid cancer
- Authors
- Jeong, J.H.; Ahn, J.Y.; Park, S.H.; Park, M.J.; Kim, K.H.; Hong, J.S.
- Issue Date
- 2012
- Keywords
- Acute myeloid leukemia; CBFβ-myh11; Eosinophilia; K-ras; Radioiodine; Thyroid cancer
- Citation
- Korean Journal of Hematology, v.47, no.3, pp.225 - 228
- Journal Title
- Korean Journal of Hematology
- Volume
- 47
- Number
- 3
- Start Page
- 225
- End Page
- 228
- ISSN
- 1738-7949
- Abstract
- Radioiodine is regularly used in the treatment of thyroid cancer to eliminate residual malignant tissue after thyroidectomy and to treat metastasis. Because of the low dose of radioiodine used to treat thyroid cancer patients, leukemia is an uncommon complication of exposure to radioiodine. Here, we present a patient who developed therapy-related acute myeloid leukemia with inv(16)(p13.1q22);CBFβ-MYH11, eosinophilia, and K-ras mutation and who had been treated with very low-dose radioiodine following total thyroidectomy. © 2012 Korean Society of Hematology.
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Related Researcher
- Ahn, Jeong Yeal
- College of Medicine (Department of Medicine)