Physiological application of nanoparticles in calcium-related proteins and channels
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Dongun | - |
dc.contributor.author | Hong, Jeong Hee | - |
dc.date.available | 2020-03-03T08:42:55Z | - |
dc.date.created | 2020-02-24 | - |
dc.date.issued | 2019-09 | - |
dc.identifier.issn | 1743-5889 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/18233 | - |
dc.description.abstract | Nanoparticles (NPs) have been studied as therapeutic drug-delivery agents for promising clinical trial outcomes. Nanomaterial-based drugs can transfer conventional drugs to target lesions, such as tumors, with increasing efficiency by enhancing drug-cell interaction or drug absorption. Although they are favorable as efficient drug transfer systems, NPs also exhibit cytotoxicity that affects nonpathological regions. Here, we review the basic information behind NP-induced Ca2+ signaling and its participation in channel physiology and pathology. NPs are observed to demonstrate inhibitory or active effects on Ca2+ signaling. Thus, understanding Ca2+ signaling by NPs as a key mechanism in signal transduction will progress the application of nano-drugs in various diseases without deleterious effect. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | FUTURE MEDICINE LTD | - |
dc.relation.isPartOf | NANOMEDICINE | - |
dc.subject | RECEPTOR KINASE 1 | - |
dc.subject | PLASMA-MEMBRANE | - |
dc.subject | DIOXIDE NANOPARTICLES | - |
dc.subject | RYANODINE RECEPTOR | - |
dc.subject | CA2+ ENTRY | - |
dc.subject | CHEMOTAXIS | - |
dc.subject | EXPRESSION | - |
dc.subject | BETA-ARRESTIN-2 | - |
dc.subject | ACTIVATION | - |
dc.subject | MECHANISM | - |
dc.title | Physiological application of nanoparticles in calcium-related proteins and channels | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000498814400007 | - |
dc.identifier.doi | 10.2217/nnm-2019-0004 | - |
dc.identifier.bibliographicCitation | NANOMEDICINE, v.14, no.18, pp.2479 - 2486 | - |
dc.identifier.scopusid | 2-s2.0-85072576055 | - |
dc.citation.endPage | 2486 | - |
dc.citation.startPage | 2479 | - |
dc.citation.title | NANOMEDICINE | - |
dc.citation.volume | 14 | - |
dc.citation.number | 18 | - |
dc.contributor.affiliatedAuthor | Lee, Dongun | - |
dc.contributor.affiliatedAuthor | Hong, Jeong Hee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Ca2+ ATPase | - |
dc.subject.keywordAuthor | Ca2+ signaling | - |
dc.subject.keywordAuthor | cytotoxicity | - |
dc.subject.keywordAuthor | G protein-coupled receptors | - |
dc.subject.keywordAuthor | nanoparticles | - |
dc.subject.keywordAuthor | signal transduction | - |
dc.subject.keywordAuthor | store-operated Ca2+ channels | - |
dc.subject.keywordAuthor | transient receptor potential channels | - |
dc.subject.keywordAuthor | voltage-gated Ca2+ channels | - |
dc.subject.keywordPlus | RECEPTOR KINASE 1 | - |
dc.subject.keywordPlus | PLASMA-MEMBRANE | - |
dc.subject.keywordPlus | DIOXIDE NANOPARTICLES | - |
dc.subject.keywordPlus | RYANODINE RECEPTOR | - |
dc.subject.keywordPlus | CA2+ ENTRY | - |
dc.subject.keywordPlus | CHEMOTAXIS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | BETA-ARRESTIN-2 | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | MECHANISM | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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