Residual Shunt after Patent Foramen Ovale Device Closure in Patients With Cryptogenic Stroke: Serial Bubble Contrast Transesophageal Echocardiography Data
- Authors
- Moon, Jeonggeun; Kim, Minsu; Oh, Pyung Chun; Shin, Dong Hoon; Park, Hyeon-M, I; Jo, Yours Yi; Lee, Ji Sung; Kang, Woong Chol
- Issue Date
- Feb-2019
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- Patent foramen ovale; PFO closure; residual shunt; bubble contrast transesophageal echocardiography
- Citation
- JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.28, no.2, pp.347 - 353
- Journal Title
- JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
- Volume
- 28
- Number
- 2
- Start Page
- 347
- End Page
- 353
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1874
- DOI
- 10.1016/j.jstrokecerebrovasdis.2018.10.006
- ISSN
- 1052-3057
- Abstract
- Background: Percutaneous closure of patent foramen ovale (PFO) is an alternative option to medical treatment for secondary prevention for cryptogenic stroke (CS). Despite technical success of procedure, residual shunt (RS) which is a presumable cause for recurrent stroke is observed in some patients. We evaluated the RS with serial follow-up bubble contrast transesophageal echocardiography (BCTEE) after PFO closure. Methods: Among consecutive 47 CS patients who underwent PFO closure, a serial follow-up BCTEE at 3 and 9 months after the index procedure was completed in 38 patients (81%, 46 +/- 10 years, 19 men). To evaluate the efficacy of PFO closure, the incidence of any and significant RS (>= moderate) was assessed. Results: All PFO closure procedures were successful. The Amplatzer PFO Occluder (n = 19) or the Gore Septal Occluder (n = 19) were used. Any RS was observed in 13 (34%) and 10 patients (26%) at 3 and 9 months after the procedure. Significant RS was observed in 6 (16%) and 4 (11%) patients at 3- and 9-month follow-up BCTEE. Patients who were treated with the Gore Septal Occluder have a less incidence of any RS in 3 months, and any/significant RS in 3- and 9-month follow-up BCTEE without statistical significance. Conclusions: RS grade keeps decreasing after PFO closure, but it remains even after 9 months in some patients. Incomplete sealing of PFO should be taken into consideration in management of CS patients even after technically successful PFO closure.
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