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Macrophages in xenotransplantation
- Authors
- 김재영
- Issue Date
- Dec-2019
- Publisher
- 대한이식학회
- Keywords
- Xenotransplantation; Macrophages; Inflammation; Coagulation
- Citation
- Korean Journal of Transplantation, v.33, no.4, pp.74 - 82
- Journal Title
- Korean Journal of Transplantation
- Volume
- 33
- Number
- 4
- Start Page
- 74
- End Page
- 82
- ISSN
- 1598-1711
- Abstract
- Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed the involvement of macrophages in xenograft and allograft rejections. Macrophages have been shown to play a critical role in inflammation, coagulation, and phagocytosis in xenograft rejection. This review presents a recent understanding of the role of macrophages in xenograft rejection and possible strategies to control macrophage-mediated xenograft rejection.
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Related Researcher
- Kim, Jae Young
- BioNano Technology (Department of Life Sciences)