Effectiveness of single-dose administration of inactivated hepatitis A virus vaccination in the Republic of Korea armed forces, 2013-2016
- Authors
- Im J.H.; Woo H.-T.; Ha B.; Jung J.
- Issue Date
- May-2020
- Publisher
- Blackwell Publishing Ltd
- Keywords
- hepatitis A; hepatitis A vaccine; military personnel; protective effectiveness; Republic of Korea; single-dose
- Citation
- Journal of Viral Hepatitis
- Journal Title
- Journal of Viral Hepatitis
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/19472
- DOI
- 10.1111/jvh.13249
- ISSN
- 1352-0504
- Abstract
- The Republic of Korea Armed Forces has implemented the hepatitis A virus (HAV) vaccination programme with a single-dose administration schedule in new recruits since 2013. A single-dose administration was selected for economic feasibility. We analysed the effectiveness of the single-dose HAV vaccination in a young and healthy population. To measure the effectiveness of the programme, we observed the incidence of HAV between the vaccinated and unvaccinated groups. A comparison between the two groups during the vaccine introduction period (2013-2016) revealed a lower incidence rate of infection in the vaccinated group (3 cases/603 550 person-years) than in the unvaccinated group (21 cases/1 020 450 person-years). The effectiveness of single-dose HAV vaccination was found to be 75.85%. © 2019 John Wiley & Sons Ltd
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