Bio-inspired green fluorescent gold-naringin nanoclusters as a dual-functional optical probe for bio-imaging and intracellular sensing applications
- Authors
- Sangubotla, Roopkumar; Lakshmi, Buddolla Anantha; Kim, Sanghyo; Kim, Jongsung
- Issue Date
- 30-Apr-2020
- Publisher
- ELSEVIER
- Keywords
- Gold-naringin nanoclusters; Hg2+; Multi-color imaging; Shrimps; Detection limit; Intracellular fluorescence sensing
- Citation
- APPLIED SURFACE SCIENCE, v.510
- Journal Title
- APPLIED SURFACE SCIENCE
- Volume
- 510
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/26068
- DOI
- 10.1016/j.apsusc.2020.145417
- ISSN
- 0169-4332
- Abstract
- Human exposure to mercury (Hg2+) happens in everyday life via exposure to aquatic animals like fishes, shrimps, and prawns. We developed bio-inspired gold-naringin nanoclusters (GNNCs) as a novel fluorescent probe for sensitive and selective detection of Hg2+ ions. GNNCs exhibit green-color emission under UV illumination with excellent selectivity for Hg2+ over other metal ions. GNNCs demonstrated excellent photostability and excitation-dependent emission behaviors. As-synthesized GNNCs facilitate Hg2+ detection in the range of 0-5 mu M with a detection limit of 26.42 nM. GNNCs also provide effective multi-color fluorescence imaging of shrimp as an animal model. GNNCs displayed excellent intracellular fluorescence sensing of Hg(2+ )and in vitro cytotoxicity in cancer (A549) cells. The practicality and feasibility of GNNCs were examined using real water samples from streams and tap water.
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Collections - 공과대학 > 화공생명공학과 > 1. Journal Articles
- 바이오나노대학 > 바이오나노학과 > 1. Journal Articles
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