Short stature is associated with incident sudden cardiac death in a large Asian cohort
- Authors
- Park Y.M.; Moon J.; Hwang I.C.; Lim H.; Cho B.
- Issue Date
- Jun-2020
- Publisher
- Elsevier B.V.
- Keywords
- Anthropometry; Asian; Height; Population-based study; Sudden cardiac death
- Citation
- Heart Rhythm, v.17, no.6, pp.931 - 936
- Journal Title
- Heart Rhythm
- Volume
- 17
- Number
- 6
- Start Page
- 931
- End Page
- 936
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/26342
- DOI
- 10.1016/j.hrthm.2020.01.026
- ISSN
- 1547-5271
- Abstract
- Background: Few data on the association between height and the risk of sudden cardiac death (SCD) in Asian populations are available. Objective: The purpose of this study was to assess the risk of SCD as related to height both in a representative Korean population and in specific subgroups. Methods: This is a retrospective cohort study of 410,119 Koreans age ≥20 years from the Korean National Health Insurance Service–National Sample Cohort, who underwent a national health examination. SCD cases were adjudicated based on information within the claims database. Cox proportional hazard models were applied to estimate hazard ratios and 95% confidence intervals for the association between height and SCD. Potential mediators included demographic factors, health-related habits, and specific cardiovascular comorbidities. Results: During an 8.45-year follow-up period, a total of 1341 SCDs occurred. Various factors, including short stature, were identified as risk factors for SCD. Multivariable regression analysis revealed that a 10-cm increase in height was associated with a 14% decreased risk for SCD. This relationship remained significant among the elderly, postmenopausal women, and individuals without cardiovascular disease. Conclusion: Our results indicate that short stature is a significant risk factor for SCD in a Korean population, thus supporting previously published findings correlating height to SCD risk in non-Asian populations. © 2020 Heart Rhythm Society
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