Efficacy and Safety of Sinetrol-XPur on Weight and Body Fat Reduction in Overweight or Obese Adults: A 12-Week, Randomized, Double-Blind, Parallel, Placebo-Controlled Trial
DC Field | Value | Language |
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dc.contributor.author | Park, Seon-Joo | - |
dc.contributor.author | Sharma, Anshul | - |
dc.contributor.author | Bae, Mun Hyoung | - |
dc.contributor.author | Sung, Ha Chang | - |
dc.contributor.author | Kim, Nam Ki | - |
dc.contributor.author | Sung, Eunju | - |
dc.contributor.author | Lee, Hae-Jeung | - |
dc.date.available | 2020-04-06T07:39:13Z | - |
dc.date.created | 2020-04-02 | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 1096-620X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/26460 | - |
dc.description.abstract | This study investigated the effect of Sinetrol-XPur on weight and body fat reduction in overweight or obese Korean participants. Among 100 overweight or obese participants enrolled in a 12-week randomized, double-blinded, controlled study, 86 participants completed the trial. Participants took either two Sinetrol-XPur tablets (450 mg per tablet) or two placebo tablets once a day. Bodyweight, body fat percentage, body mass index (BMI), body fat mass, waist circumference, and various safety parameters were measured. After the 12-week intervention, a significant reduction was observed in the body fat mass (P = .030) by dual-energy X-ray absorptiometry (DEXA), body weight (P = .002), and BMI (P = .002) compared to the placebo. Body fat percentage (P = .007) by DEXA showed a significant reduction in the Sinetrol-XPur group, but no difference compared to the control group. Abdominal metabolic risks by computed tomography and blood biochemistry analysis were significantly decreased in the Sinetrol-XPur group, but there were no differences between the Sinetrol-XPur and placebo groups. Safety profiles were not different between the two groups. These results suggested that Sinetrol-XPur significantly reduced body weight, body fat mass, and BMI in obese Korean subjects, which confirms the antiobesity effect of Sinetrol-XPur in the Korean population. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.relation.isPartOf | JOURNAL OF MEDICINAL FOOD | - |
dc.title | Efficacy and Safety of Sinetrol-XPur on Weight and Body Fat Reduction in Overweight or Obese Adults: A 12-Week, Randomized, Double-Blind, Parallel, Placebo-Controlled Trial | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000517959200001 | - |
dc.identifier.doi | 10.1089/jmf.2019.4649 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MEDICINAL FOOD, v.23, no.3, pp.335 - 342 | - |
dc.identifier.kciid | ART002570056 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85082143265 | - |
dc.citation.endPage | 342 | - |
dc.citation.startPage | 335 | - |
dc.citation.title | JOURNAL OF MEDICINAL FOOD | - |
dc.citation.volume | 23 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Park, Seon-Joo | - |
dc.contributor.affiliatedAuthor | Sharma, Anshul | - |
dc.contributor.affiliatedAuthor | Lee, Hae-Jeung | - |
dc.type.docType | Article; Early Access | - |
dc.subject.keywordAuthor | body fat mass | - |
dc.subject.keywordAuthor | body mass index | - |
dc.subject.keywordAuthor | bodyweight | - |
dc.subject.keywordAuthor | obesity | - |
dc.subject.keywordAuthor | Sinetrol-XPur | - |
dc.subject.keywordPlus | ORANGE SINETROL | - |
dc.subject.keywordPlus | RED ORANGE | - |
dc.subject.keywordPlus | GRAPEFRUIT | - |
dc.subject.keywordPlus | PHOSPHODIESTERASE | - |
dc.subject.keywordPlus | HEALTHY | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | MASS | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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